ARMC5

Across TCGA cell cohorts, ARMC5 mutation is significantly associated with the RNA expression of many other genes, with 141 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARMC5-associated genes across cancer lineages are ADAM18, PNLIPRP3, and GABRA4. Each is linked with ARMC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARMC5-to-partner and partner-to-ARMC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM18 grouped by ARMC5-low versus ARMC5-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARMC5→partner) and Y-score (partner→ARMC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ADAM18 →	+0.101	+4.201	<.001	.003	3	2
BLOOD_Leukemia	PNLIPRP3 →	+0.008	+2.966	<.001	.005	3	2
OESOPHAGUS	GABRA4 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	TXNDC8 →	+0.016	+4.906	<.001	.006	3	1
OVARY	OR2AK2 →	+0.062	+4.029	<.001	.009	3	1
OVARY	OR2T4 →	+0.025	+4.807	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 141 associations by consensus.

ADAM18 by ARMC5 expression — CNS

Explore this box plot interactively →