ARL6IP6

Across TCGA patient cohorts, ARL6IP6 mutation is significantly associated with the RNA expression of many other genes, with 488 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible ARL6IP6-associated genes across cancer lineages are NIPA2P3, OR10Z1, and RNU7-130P. Each is linked with ARL6IP6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARL6IP6-to-partner and partner-to-ARL6IP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NIPA2P3 grouped by ARL6IP6-low versus ARL6IP6-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL6IP6→partner) and Y-score (partner→ARL6IP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	NIPA2P3 →	+0.089	+5.450	<.001	.004	3	3
ESCA	OR10Z1 →	+0.172	+5.247	.006	.006	3	3
COAD	RNU7-130P →	+1.391	+7.409	<.001	<.001	3	2
COAD	RN7SL250P →	+0.520	+5.693	<.001	.003	3	2
COAD	UBFD1P1 →	+0.195	+6.721	<.001	<.001	3	2
COAD	RNU4-49P →	+1.655	+5.435	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 488 associations by consensus.

NIPA2P3 by ARL6IP6 expression — ESCA

Explore this box plot interactively →