ARL5B

Across TCGA patient cohorts, ARL5B protein abundance is significantly associated with the RNA expression of many other genes, with 8,582 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ARL5B-associated genes across cancer lineages are CASQ2, CRBN, and ARHGEF6. Each is linked with ARL5B in more than 4 cancer types. Because this analysis shows association rather than direction, both ARL5B-to-partner and partner-to-ARL5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARL5B versus CASQ2 in CCRCC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL5B→partner) and Y-score (partner→ARL5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	CASQ2 →	-1.486	-0.289	.002	.001	3	5
BRCA	CRBN →	-0.471	-0.270	<.001	<.001	3	4
BRCA	ARHGEF6 →	-0.961	-0.589	<.001	<.001	3	4
GBM	ANK2 →	-0.917	-0.679	.001	.005	3	4
BRCA	PPM1M →	-0.416	-0.388	.004	.001	3	4
LUAD	VEGFD →	-0.785	-0.290	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,582 associations by consensus.

ARL5B vs CASQ2 — CCRCC

Explore this scatter interactively →