ARL14EPL

Across TCGA patient cohorts, ARL14EPL mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SCLC shows the largest number of these associations.

The most reproducible ARL14EPL-associated genes across cancer lineages are KLK5 and PFN3. Each is linked with ARL14EPL in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL14EPL-to-partner and partner-to-ARL14EPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KLK5 grouped by ARL14EPL-low versus ARL14EPL-high in SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL14EPL→partner) and Y-score (partner→ARL14EPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	KLK5 →	+0.378	+4.847	<.001	.009	3	1
SCLC	PFN3 →	+0.226	+4.847	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

KLK5 by ARL14EPL expression — SCLC

Explore this box plot interactively →