ARL14EP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARL14EP protein abundance is significantly associated with the RNA expression of many other genes, with 13,490 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARL14EP-associated genes across cancer lineages are SERPINE1, NEK2, and CENPF. Each is linked with ARL14EP in more than 4 cancer types. Because this analysis shows association rather than direction, both ARL14EP-to-partner and partner-to-ARL14EP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARL14EP versus SERPINE1 in GBM, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL14EP→partner) and Y-score (partner→ARL14EP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSERPINE1 →-1.308-0.201<.001<.00135
GBMNEK2 →+1.017+0.280<.001.00135
GBMCENPF →+1.343+0.378<.001<.00135
UCECCKS2 →+1.103+0.202<.001<.00135
HNSCHROB →+0.862+0.174<.001.00635
UCECCCDC150 →+0.764+0.180<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,490 associations by consensus.

ARL14EP vs SERPINE1 — GBM

Per-sample scatter of ARL14EP vs SERPINE1 in GBM (Pearson r = -0.40).

Explore this scatter interactively →

Exploration