ARL14EP

Across TCGA cell cohorts, ARL14EP mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARL14EP-associated genes across cancer lineages are KRTAP5-6 and SLC39A12. Each is linked with ARL14EP in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL14EP-to-partner and partner-to-ARL14EP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP5-6 grouped by ARL14EP-low versus ARL14EP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL14EP→partner) and Y-score (partner→ARL14EP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KRTAP5-6 →	+0.420	+3.473	<.001	.008	3	1
LARGE_INTESTINE	SLC39A12 →	+0.102	+3.700	<.001	.004	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

KRTAP5-6 by ARL14EP expression — LARGE_INTESTINE

Explore this box plot interactively →