ARL10

Across TCGA patient cohorts, ARL10 mutation is significantly associated with the RNA expression of many other genes, with 256 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARL10-associated genes across cancer lineages are TSPY15P, OR5J7P, and TRAJ12. Each is linked with ARL10 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARL10-to-partner and partner-to-ARL10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSPY15P grouped by ARL10-low versus ARL10-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARL10→partner) and Y-score (partner→ARL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TSPY15P →	+0.049	+7.731	<.001	.009	3	2
SKCM	OR5J7P →	+0.073	+5.408	<.001	.002	3	2
UCEC	TRAJ12 →	+0.525	+2.166	.005	.008	3	2
BRCA	TTTY7B →	+0.024	+8.471	<.001	.005	3	1
BRCA	RNU6ATAC19P →	+0.759	+7.731	<.001	.009	3	1
UCEC	CWC25 →	+0.443	+2.617	.007	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 256 associations by consensus.

TSPY15P by ARL10 expression — BRCA

Explore this box plot interactively →