ARL10

Across TCGA pan-cancer cohorts, ARL10 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated ARL10 data layer compared with 1 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher ARL10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ARL10 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SCLC show a favorable association.

MESO, OV, and LIHC are the cancer types where ARL10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.253	0.549	<.001	93	view →
OV	DFS	Median	III,IV	0.480	0.580	.003	68	view →
LIHC	OS	Tertile	All	0.684	0.869	.001	46	view →
ACC	DFS	Median	All	0.284	0.758	<.001	42	view →
KIRC	DFS	Tertile	All	0.926	0.839	<.001	40	view →
UCEC	OS	Median	All	0.632	0.707	.008	32	view →
BLCA	DFS	Quartile	II,III,IV	0.422	0.567	.008	31	view →
SCLC	DFS	Tertile	II,III,IV	1.000	0.332	.006	31	view →
COAD	DFS	Tertile	All	0.289	0.610	.007	24	view →
GBM	OS	Median	All	0.528	0.285	.005	18	view →
DLBC	DFS	Median	All	0.672	1.000	.036	13	view →
STAD	DFS	Tertile	All	0.327	0.559	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

ARL10–MESO (OS)

Open the MESO breakdown →