ARL10

Across TCGA pan-cancer cohorts, ARL10 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ARL10’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ARL10 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ARL10 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KIRC, LIHC, and KICH are the cancer types where ARL10 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARL10 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	+1.008	<.001	11	view →
LIHC	All	II,III,IV	+0.322	<.001	8	view →
KICH	Female	All	−0.839	<.001	6	view →
BRCA	All	All	−0.567	<.001	6	view →
LUSC	Male	II,III,IV	+0.749	<.001	4	view →
CHOL	All	All	+0.917	.001	3	view →
UCEC	All	All	−1.067	<.001	2	view →
PRAD	All	All	−0.470	<.001	2	view →
HNSC	Male	All	+0.403	.021	2	view →
BLCA	All	IV	−0.727	.047	1	view →
LUAD	All	All	+0.241	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ARL10–KIRC

Open the KIRC breakdown →