Across TCGA patient cohorts, ARID5A mutation is significantly associated with the RNA expression of many other genes, with 1,202 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARID5A-associated genes across cancer lineages are TKFC, CHEK1, and ZC3H18. Each is linked with ARID5A in more than 1 cancer types. Because this analysis shows association rather than direction, both ARID5A-to-partner and partner-to-ARID5A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID5A→partner) and Y-score (partner→ARID5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TKFC →	+0.409	+2.098	.003	.003	3	2
UCEC	CHEK1 →	+0.581	+2.246	.004	.005	3	2
UCEC	ZC3H18 →	+0.432	+2.617	.001	<.001	3	2
UCEC	STOML2 →	+0.409	+2.740	.008	.003	3	2
UCEC	GPT2 →	+0.728	+2.606	<.001	<.001	3	2
UCEC	CENPN →	+0.595	+3.700	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,202 associations by consensus.

Exploration

ARID5A survival (RNA) · tumor vs normal (RNA) · all ARID5A data types