Across TCGA patient cohorts, ARID5A mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARID5A-associated genes across cancer lineages are 14-3-3_beta, Fibronectin, and Ku80. Each is linked with ARID5A in more than 1 cancer types. Because this analysis shows association rather than direction, both ARID5A-to-partner and partner-to-ARID5A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID5A→partner) and Y-score (partner→ARID5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.111	-3.295	.011	.009	3	2
UCEC	Fibronectin →	-0.342	-2.449	.017	.019	3	1
UCEC	Ku80 →	+0.344	+2.128	<.001	.010	3	1
UCEC	Myosin-IIa_pS1943 →	+0.202	+1.598	.025	.044	3	1
UCEC	Notch1 →	+0.218	+1.887	<.001	.029	3	1
UCEC	p27_pT157 →	-0.056	-2.115	.026	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

ARID5A survival (RNA) · tumor vs normal (RNA) · all ARID5A data types