Across TCGA cell cohorts, ARID5A mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARID5A-associated genes across cancer lineages are MROH2B, TMEM244, and CPXCR1. Each is linked with ARID5A in more than 1 cancer types. Because this analysis shows association rather than direction, both ARID5A-to-partner and partner-to-ARID5A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID5A→partner) and Y-score (partner→ARID5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MROH2B →	+0.004	+4.415	<.001	.007	3	1
LARGE_INTESTINE	TMEM244 →	+0.515	+4.415	<.001	.007	3	1
BLOOD_Leukemia	CPXCR1 →	+0.059	+3.971	.004	.002	3	1
BLOOD_Leukemia	FAM24A →	+0.042	+3.969	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.028	+3.969	<.001	.009	3	1
BLOOD_Leukemia	SCT →	+0.266	+3.906	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

ARID5A survival (RNA) · tumor vs normal (RNA) · all ARID5A data types