Across TCGA patient cohorts, ARID2 mutation is significantly associated with the RNA expression of many other genes, with 7,266 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARID2-associated genes across cancer lineages are SLC17A5, QPCT, and DNAAF3. Each is linked with ARID2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ARID2-to-partner and partner-to-ARID2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID2→partner) and Y-score (partner→ARID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SLC17A5 →	+0.543	+1.734	<.001	<.001	3	5
STAD	QPCT →	-1.163	-3.700	.002	.001	3	4
STAD	DNAAF3 →	+1.030	+3.733	<.001	<.001	3	4
UCEC	ZBTB8OS →	+0.374	+1.724	<.001	<.001	3	4
UCEC	DNAJC25 →	+0.519	+1.415	<.001	<.001	3	4
READ	OR51C1P →	+0.067	+3.469	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,266 associations by consensus.

Exploration

ARID2 survival (RNA) · tumor vs normal (RNA) · all ARID2 data types