Across TCGA cell cohorts, ARID2 mutation is significantly associated with the RNA expression of many other genes, with 1,359 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARID2-associated genes across cancer lineages are GCFC2, TCF15, and HTR6. Each is linked with ARID2 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARID2-to-partner and partner-to-ARID2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARID2→partner) and Y-score (partner→ARID2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GCFC2 →	+0.594	+2.850	.001	<.001	3	3
LUNG_NSCLC_LUAD	TCF15 →	+0.335	+2.834	<.001	.004	3	2
LUNG_NSCLC_LUAD	HTR6 →	+0.196	+3.466	<.001	.005	3	2
LARGE_INTESTINE	BLOC1S6 →	+0.388	+2.158	.007	.004	3	2
LARGE_INTESTINE	TLE6 →	+0.981	+2.850	<.001	<.001	3	2
LARGE_INTESTINE	FAM172A →	+0.534	+2.158	.008	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,359 associations by consensus.

Exploration

ARID2 survival (RNA) · tumor vs normal (RNA) · all ARID2 data types