ARHGEF7-IT1

Across TCGA patient cohorts, ARHGEF7-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,787 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGEF7-IT1-associated proteins across cancer lineages are ARHGEF7_S25, PEAK1, and HDGFL3. Each is linked with ARHGEF7-IT1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ARHGEF7-IT1-to-partner and partner-to-ARHGEF7-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF7-IT1 versus ARHGEF7_S25 in GBM, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF7-IT1→partner) and Y-score (partner→ARHGEF7-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGEF7_S25 →	+0.898	+1.164	<.001	<.001	3	7
UCEC	PEAK1 →	+0.329	+0.762	<.001	<.001	3	6
UCEC	HDGFL3 →	+0.787	+0.587	<.001	<.001	3	6
GBM	TMOD2 →	+0.390	+0.639	<.001	<.001	3	5
UCEC	MSRB3 →	+1.005	+0.684	<.001	<.001	3	5
CCRCC	PRKG1 →	+0.551	+0.558	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,787 associations by consensus.

ARHGEF7-IT1 vs ARHGEF7_S25 — GBM

Explore this scatter interactively →