ARHGEF40

Across TCGA patient cohorts, ARHGEF40 protein abundance is significantly associated with the RNA expression of many other genes, with 12,157 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGEF40-associated genes across cancer lineages are CARMN, TIMP3, and NFATC4. Each is linked with ARHGEF40 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARHGEF40-to-partner and partner-to-ARHGEF40 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF40 versus CARMN in UCEC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF40→partner) and Y-score (partner→ARHGEF40) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CARMN →	+1.260	+0.277	<.001	<.001	3	6
UCEC	TIMP3 →	+1.311	+0.211	<.001	<.001	3	5
BRCA	NFATC4 →	+1.067	+0.237	<.001	.001	3	5
BRCA	TTK →	-0.995	-0.204	<.001	.001	3	5
UCEC	CENPF →	-1.152	-0.203	<.001	.002	3	5
BRCA	NCAPH →	-0.787	-0.251	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,157 associations by consensus.

ARHGEF40 vs CARMN — UCEC

Explore this scatter interactively →