ARHGEF25

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARHGEF25 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,029 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ARHGEF25-associated proteins across cancer lineages are VCAN, VCL_S346, and RAB23. Each is linked with ARHGEF25 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARHGEF25-to-partner and partner-to-ARHGEF25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGEF25 versus VCAN in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF25→partner) and Y-score (partner→ARHGEF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCVCAN →+1.047+0.625<.001<.00139
LSCCVCL_S346 →+0.605+0.608<.001<.00139
COADRAB23 →+0.512+0.519<.001<.00139
BRCASERPINF1 →+0.830+0.631<.001<.00139
LUADSGCD →+0.579+0.433<.001<.00139
HNSCPCOLCE →+0.667+0.579.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,029 associations by consensus.

ARHGEF25 vs VCAN — HNSC

Per-sample scatter of ARHGEF25 vs VCAN in HNSC (Pearson r = 0.35).

Explore this scatter interactively →

Exploration