ARHGEF25

Across TCGA cell cohorts, ARHGEF25 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,352 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ARHGEF25-associated GO terms across cancer lineages are Lipoprotein localization, Lipoprotein transport, and Ribose phosphate biosynthetic process. Each is linked with ARHGEF25 in more than 14 cancer types. Because this analysis shows association rather than direction, both ARHGEF25-to-partner and partner-to-ARHGEF25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipoprotein localization grouped by ARHGEF25-low versus ARHGEF25-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGEF25→partner) and Y-score (partner→ARHGEF25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Lipoprotein localization →	+0.187	+1.886	<.001	<.001	3	15
OVARY	Lipoprotein transport →	+0.186	+1.789	<.001	<.001	3	15
OESOPHAGUS	Ribose phosphate biosynthetic process →	+0.096	+2.394	<.001	<.001	3	13
SKIN	DNA-templated transcription initiation →	+0.063	+1.761	<.001	<.001	3	13
STOMACH	tRNA transcription by RNA polymerase III →	+0.135	+2.973	.001	<.001	3	13
STOMACH	Negative regulation of myoblast fusion →	+0.171	+2.929	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,352 associations by consensus.

Lipoprotein localization by ARHGEF25 expression — OVARY

Explore this box plot interactively →