ARHGDIG

Across TCGA patient cohorts, ARHGDIG protein abundance is significantly associated with the RNA expression of many other genes, with 64 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGDIG-associated genes across cancer lineages are SLC38A7, STX12, and MRPS14. Each is linked with ARHGDIG in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGDIG-to-partner and partner-to-ARHGDIG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGDIG versus SLC38A7 in GBM, with a Pearson correlation of -0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGDIG→partner) and Y-score (partner→ARHGDIG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC38A7 →	-0.415	-0.569	.005	.009	3	1
GBM	STX12 →	+0.488	+0.828	.001	.008	3	1
GBM	MRPS14 →	+0.396	+0.481	.004	.004	3	1
GBM	IER3IP1 →	+0.748	+0.560	.006	.004	3	1
GBM	SPATA22 →	+0.723	+0.519	.006	.005	3	1
GBM	RETREG3 →	-0.431	-0.830	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

ARHGDIG vs SLC38A7 — GBM

Explore this scatter interactively →