ARHGAP26

Across TCGA patient cohorts, ARHGAP26 mutation is significantly associated with the RNA expression of many other genes, with 2,965 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP26-associated genes across cancer lineages are TMEM225, FAM204DP, and SLC20A1P3. Each is linked with ARHGAP26 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARHGAP26-to-partner and partner-to-ARHGAP26 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM225 grouped by ARHGAP26-low versus ARHGAP26-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP26→partner) and Y-score (partner→ARHGAP26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	TMEM225 →	+0.114	+5.039	<.001	.008	3	3
COAD	FAM204DP →	+0.193	+4.408	<.001	<.001	3	3
COAD	SLC20A1P3 →	+0.060	+4.917	.004	.003	3	3
KIRP	NIPA2P5 →	+0.082	+5.928	<.001	.002	3	3
UCEC	PSMB7 →	+0.268	+3.098	.002	<.001	3	3
BLCA	MTND5P35 →	+0.037	+3.566	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,965 associations by consensus.

TMEM225 by ARHGAP26 expression — READ

Explore this box plot interactively →