ARHGAP21

Across TCGA patient cohorts, ARHGAP21 protein abundance is significantly associated with the RNA expression of many other genes, with 8,737 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP21-associated genes across cancer lineages are CCNY, PRTFDC1, and STAM. Each is linked with ARHGAP21 in more than 5 cancer types. Because this analysis shows association rather than direction, both ARHGAP21-to-partner and partner-to-ARHGAP21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP21 versus CCNY in HNSC, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP21→partner) and Y-score (partner→ARHGAP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CCNY →	+0.442	+0.240	.009	.006	3	6
BRCA	PRTFDC1 →	+1.082	+0.319	<.001	<.001	3	6
GBM	STAM →	+0.510	+0.300	<.001	<.001	3	5
LSCC	ABI1 →	+0.423	+0.221	<.001	<.001	3	5
LSCC	MINDY3 →	+0.527	+0.233	<.001	<.001	3	5
GBM	ZMYND11 →	+0.517	+0.258	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,737 associations by consensus.

ARHGAP21 vs CCNY — HNSC

Explore this scatter interactively →