ARHGAP21

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ARHGAP21 protein abundance is significantly associated with the RNA expression of many other genes, with 3,756 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible ARHGAP21-associated genes across cancer lineages are ATP5F1D, UQCRC1, and SKIL. Each is linked with ARHGAP21 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARHGAP21-to-partner and partner-to-ARHGAP21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP21 versus ATP5F1D in STOMACH, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP21→partner) and Y-score (partner→ARHGAP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHATP5F1D →+1.333+0.861.002.00739
BLOOD_MyelomaUQCRC1 →+0.685+0.407.005.00536
STOMACHSKIL →-2.846-0.738<.001.00336
STOMACHUQCR11 →+1.065+0.731.003.00336
CNSCPNE7 →+1.941+0.626.002.00735
LUNG_NSCLC_LUSCSOD1 →+1.104+1.111.003.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,756 associations by consensus.

ARHGAP21 vs ATP5F1D — STOMACH

Per-sample scatter of ARHGAP21 vs ATP5F1D in STOMACH (Pearson r = 0.57).

Explore this scatter interactively →

Exploration