ARHGAP12

Across TCGA patient cohorts, ARHGAP12 mutation is significantly associated with the RNA expression of many other genes, with 5,138 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP12-associated genes across cancer lineages are RNF19BPY, OR8G1, and RNU6-604P. Each is linked with ARHGAP12 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARHGAP12-to-partner and partner-to-ARHGAP12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNF19BPY grouped by ARHGAP12-low versus ARHGAP12-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP12→partner) and Y-score (partner→ARHGAP12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNF19BPY →	+0.027	+4.707	<.001	<.001	3	3
STAD	OR8G1 →	+0.154	+3.156	<.001	.006	3	3
HNSC	RNU6-604P →	+0.471	+5.608	<.001	.002	3	3
BRCA	OR14I1 →	+0.118	+4.892	<.001	.002	3	3
LUAD	NPM1P4 →	+0.101	+3.423	<.001	.006	3	3
LUAD	RPL32P13 →	+0.190	+3.689	.009	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,138 associations by consensus.

RNF19BPY by ARHGAP12 expression — BLCA

Explore this box plot interactively →