ARG1

Across TCGA patient cohorts, ARG1 mutation is significantly associated with the RNA expression of many other genes, with 439 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARG1-associated genes across cancer lineages are MIR6854, MIR4663, and RNA5SP414. Each is linked with ARG1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARG1-to-partner and partner-to-ARG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6854 grouped by ARG1-low versus ARG1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARG1→partner) and Y-score (partner→ARG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR6854 →	+0.445	+5.251	.002	.006	3	3
LUSC	MIR4663 →	+0.495	+5.337	<.001	.006	3	2
UCEC	RNA5SP414 →	+0.429	+2.255	.006	.009	3	2
UCEC	MIR520H →	+0.237	+3.582	<.001	.002	3	2
UCEC	RNA5SP419 →	+0.582	+2.492	.001	.002	3	2
SKCM	FABP12 →	+0.129	+3.403	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 439 associations by consensus.

MIR6854 by ARG1 expression — BLCA

Explore this box plot interactively →