ARG1

Across TCGA cell cohorts, ARG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,690 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARG1-associated GO terms across cancer lineages are Negative regulation of T-helper 2 cell cytokine production, Regulation of organelle assembly, and Positive regulation of TORC1 signaling. Each is linked with ARG1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ARG1-to-partner and partner-to-ARG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of T-helper 2 cell cytokine production grouped by ARG1-low versus ARG1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARG1→partner) and Y-score (partner→ARG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of T-helper 2 cell cytokine production →	+1.432	+2.352	.008	.001	3	14
LUNG_SCLC	Regulation of organelle assembly →	+0.043	+0.174	<.001	<.001	3	8
STOMACH	Positive regulation of TORC1 signaling →	+0.090	+0.174	<.001	.001	3	7
LUNG_NSCLC_LUSC	Vesicle fusion →	+0.080	+0.148	<.001	<.001	3	6
BONE	Positive regulation of monoatomic ion transport →	-0.121	-0.143	.001	.006	3	6
BONE	Hair follicle placode formation →	+0.055	+0.167	.007	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,690 associations by consensus.

Negative regulation of T-helper 2 cell cytokine production by ARG1 expression — LIVER

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