Across TCGA patient cohorts, ARAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,733 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARAP1-associated genes across cancer lineages are CD33, IL10RA, and SLC15A3. Each is linked with ARAP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARAP1-to-partner and partner-to-ARAP1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARAP1→partner) and Y-score (partner→ARAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CD33 →	+0.676	+0.270	<.001	<.001	3	7
GBM	IL10RA →	+0.804	+0.228	<.001	<.001	3	7
HNSC	SLC15A3 →	+0.832	+0.204	.001	.006	2	8
CCRCC	RAC2 →	+0.854	+0.187	<.001	<.001	3	7
GBM	LSP1 →	+0.833	+0.287	<.001	<.001	3	7
GBM	ITGAX →	+1.168	+0.329	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,733 associations by consensus.

Exploration

ARAP1 survival (RNA) · tumor vs normal (RNA) · all ARAP1 data types