Across TCGA cell cohorts, ARAP1 mutation is significantly associated with the RNA expression of many other genes, with 869 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARAP1-associated genes across cancer lineages are FAM160A1, MT3, and SPATA31D1. Each is linked with ARAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARAP1-to-partner and partner-to-ARAP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARAP1→partner) and Y-score (partner→ARAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM160A1 →	+0.771	+3.295	.002	.003	3	2
LARGE_INTESTINE	MT3 →	+1.721	+3.169	<.001	.009	3	2
BREAST	SPATA31D1 →	+0.012	+4.781	<.001	.003	3	2
PANCREAS	HEPN1 →	+0.011	+4.491	.002	.003	3	1
BLOOD_Lymphoma	KRTAP4-1 →	+0.151	+4.867	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR4K1 →	+0.012	+3.813	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 869 associations by consensus.

Exploration

ARAP1 survival (RNA) · tumor vs normal (RNA) · all ARAP1 data types