Across TCGA patient cohorts, AQP12B mutation is significantly associated with the RNA expression of many other genes, with 394 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AQP12B-associated genes across cancer lineages are RN7SKP188, RN7SL563P, and RNA5SP93. Each is linked with AQP12B in more than 2 cancer types. Because this analysis shows association rather than direction, both AQP12B-to-partner and partner-to-AQP12B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP12B→partner) and Y-score (partner→AQP12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SKP188 →	+0.130	+6.906	.007	<.001	3	3
COAD	RN7SL563P →	+0.654	+5.693	<.001	.003	3	3
UCEC	RNA5SP93 →	+0.252	+4.049	<.001	.008	3	3
LUSC	OR10AA1P →	+0.103	+5.273	<.001	.006	3	2
CESC	MIR875 →	+0.444	+5.418	<.001	.005	3	2
CESC	HMGA1P7 →	+0.082	+5.539	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 394 associations by consensus.

Exploration

AQP12B survival (RNA) · tumor vs normal (RNA) · all AQP12B data types