APOOP4

Across TCGA patient cohorts, APOOP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,907 significant associations in total. STAD shows the largest number of these associations.

The most reproducible APOOP4-associated GO terms across cancer lineages are Proton transmembrane transport, Pyrimidine ribonucleotide biosynthetic process, and Aerobic respiration. Each is linked with APOOP4 in more than 8 cancer types. Because this analysis shows association rather than direction, both APOOP4-to-partner and partner-to-APOOP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton transmembrane transport grouped by APOOP4-low versus APOOP4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APOOP4→partner) and Y-score (partner→APOOP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Proton transmembrane transport →	+0.037	+0.115	<.001	<.001	3	9
STAD	Pyrimidine ribonucleotide biosynthetic process →	+0.033	+0.090	<.001	<.001	3	9
ESCA	Aerobic respiration →	+0.056	+0.196	.003	.003	2	9
STAD	Pyrimidine ribonucleoside triphosphate biosynthetic process →	+0.036	+0.115	<.001	<.001	3	8
ESCA	Mitochondrial translation →	+0.056	+0.240	.002	<.001	3	7
ESCA	Oxidative phosphorylation →	+0.056	+0.189	.003	.005	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,907 associations by consensus.

Proton transmembrane transport by APOOP4 expression — STAD

Explore this box plot interactively →