APOOP2

Across TCGA patient cohorts, APOOP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,653 significant associations in total. STAD shows the largest number of these associations.

The most reproducible APOOP2-associated GO terms across cancer lineages are Anaphase-promoting complex-dependent catabolic process, Positive regulation of spindle assembly, and Regulation of nuclear division. Each is linked with APOOP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both APOOP2-to-partner and partner-to-APOOP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Anaphase-promoting complex-dependent catabolic process grouped by APOOP2-low versus APOOP2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APOOP2→partner) and Y-score (partner→APOOP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Anaphase-promoting complex-dependent catabolic process →	+0.084	+0.065	<.001	.002	2	5
STAD	Positive regulation of spindle assembly →	+0.087	+0.066	<.001	.004	3	4
STAD	Regulation of nuclear division →	+0.086	+0.055	<.001	.003	3	4
STAD	Cytoplasmic sequestering of NF-kappaB →	+0.090	+0.038	<.001	.002	3	4
UCEC	Mismatch repair →	+0.024	+0.120	<.001	<.001	3	4
LGG	Regulation of endocytic recycling →	+0.049	+0.008	.001	.002	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,653 associations by consensus.

Anaphase-promoting complex-dependent catabolic process by APOOP2 expression — STAD

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