APOOP2

Across TCGA pan-cancer cohorts, APOOP2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of APOOP2’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where APOOP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types APOOP2 is over-expressed in tumor, although a few such as LUAD show the opposite, repressed pattern.

BLCA, BRCA, and LUAD are the cancer types where APOOP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in APOOP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Female	IV	+1.376	.010	5	view →
BRCA	Female	All	+0.044	.034	2	view →
LUAD	All	All	−0.027	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

APOOP2–BLCA

Open the BLCA breakdown →