APOLD1

Across TCGA patient cohorts, APOLD1 mutation is significantly associated with the RNA expression of many other genes, with 334 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible APOLD1-associated genes across cancer lineages are MIR6780B, RNU6-1067P, and RNA5SP367. Each is linked with APOLD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both APOLD1-to-partner and partner-to-APOLD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6780B grouped by APOLD1-low versus APOLD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOLD1→partner) and Y-score (partner→APOLD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6780B →	+0.373	+2.719	<.001	.006	3	2
SKCM	RNU6-1067P →	+0.605	+4.500	<.001	.005	3	2
BLCA	RNA5SP367 →	+0.344	+5.038	.001	.009	3	2
SKCM	SNORD126 →	+0.512	+4.953	<.001	.002	3	1
BLCA	RN7SL66P →	+0.257	+5.177	<.001	.007	3	1
BLCA	MIR6842 →	+0.768	+5.177	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 334 associations by consensus.

MIR6780B by APOLD1 expression — UCEC

Explore this box plot interactively →