APOC3

Across TCGA patient cohorts, APOC3 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,081 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible APOC3-associated proteins across cancer lineages are SELENOP, SERPINA1, and SERPINA10. Each is linked with APOC3 in more than 9 cancer types. Because this analysis shows association rather than direction, both APOC3-to-partner and partner-to-APOC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APOC3 versus SELENOP in OV, with a Pearson correlation of 0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APOC3→partner) and Y-score (partner→APOC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SELENOP →	+0.695	+0.793	<.001	<.001	3	10
BRCA	SERPINA1 →	+0.763	+0.866	<.001	<.001	3	10
CCRCC	SERPINA10 →	+0.736	+0.893	<.001	<.001	3	10
CCRCC	SERPINA3 →	+0.716	+0.789	<.001	<.001	3	10
CCRCC	SERPINA4 →	+0.814	+0.983	<.001	<.001	3	10
CCRCC	SERPINA6 →	+0.737	+0.947	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,081 associations by consensus.

APOC3 vs SELENOP — OV

Explore this scatter interactively →