APOC1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, APOC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,810 significant associations in total. GBM shows the largest number of these associations.

The most reproducible APOC1-associated proteins across cancer lineages are ITGAX, LCP2, and PARVG. Each is linked with APOC1 in more than 9 cancer types. Because this analysis shows association rather than direction, both APOC1-to-partner and partner-to-APOC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APOC1 versus ITGAX in GBM, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APOC1→partner) and Y-score (partner→APOC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMITGAX →+0.689+1.270<.001<.001310
HNSCLCP2 →+0.429+1.233.001.001310
GBMPARVG →+0.589+1.011<.001<.001310
OVDOCK10 →+0.472+1.338<.001<.00139
UCECEVL →+0.716+1.869<.001<.00139
GBMFCER1G →+0.697+0.995<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,810 associations by consensus.

APOC1 vs ITGAX — GBM

Per-sample scatter of APOC1 vs ITGAX in GBM (Pearson r = 0.74).

Explore this scatter interactively →

Exploration