APOC1

Across TCGA cell cohorts, APOC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,587 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible APOC1-associated GO terms across cancer lineages are Chylomicron remnant clearance, Triglyceride-rich lipoprotein particle clearance, and Very-low-density lipoprotein particle clearance. Each is linked with APOC1 in more than 18 cancer types. Because this analysis shows association rather than direction, both APOC1-to-partner and partner-to-APOC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chylomicron remnant clearance grouped by APOC1-low versus APOC1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APOC1→partner) and Y-score (partner→APOC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Chylomicron remnant clearance →	+1.762	+2.580	<.001	<.001	3	19
OESOPHAGUS	Triglyceride-rich lipoprotein particle clearance →	+1.762	+2.580	<.001	<.001	3	19
PANCREAS	Very-low-density lipoprotein particle clearance →	+1.625	+2.787	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Negative regulation of phospholipid metabolic process →	+0.200	+2.037	<.001	<.001	3	14
LIVER	Cholesterol efflux →	+0.221	+4.352	<.001	<.001	3	14
BLOOD_Leukemia	Phospholipid efflux →	+0.407	+6.580	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,587 associations by consensus.

Chylomicron remnant clearance by APOC1 expression — OESOPHAGUS

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