APOA5

Across TCGA patient cohorts, APOA5 protein abundance is significantly associated with the RNA expression of many other genes, with 3,194 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible APOA5-associated genes across cancer lineages are CCN2, CALHM2, and KLHL30. Each is linked with APOA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both APOA5-to-partner and partner-to-APOA5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APOA5 versus CCN2 in LUAD, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOA5→partner) and Y-score (partner→APOA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CCN2 →	+1.091	+0.362	<.001	.008	3	3
CCRCC	CALHM2 →	+0.648	+0.654	<.001	<.001	3	2
CCRCC	KLHL30 →	+0.343	+0.577	.002	<.001	3	2
GBM	TSEN54 →	+0.337	+0.516	.006	.003	3	2
GBM	IFITM1 →	+1.192	+0.449	.001	.001	3	2
PDAC	HLA-B →	+0.746	+0.816	.008	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,194 associations by consensus.

APOA5 vs CCN2 — LUAD

Explore this scatter interactively →