APOA2

Across TCGA patient cohorts, APOA2 protein abundance is significantly associated with the RNA expression of many other genes, with 11,026 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible APOA2-associated genes across cancer lineages are LYVE1, CXCL12, and CD93. Each is linked with APOA2 in more than 6 cancer types. Because this analysis shows association rather than direction, both APOA2-to-partner and partner-to-APOA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APOA2 versus LYVE1 in BRCA, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOA2→partner) and Y-score (partner→APOA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LYVE1 →	+1.721	+0.915	<.001	<.001	3	7
BRCA	CXCL12 →	+1.233	+0.830	<.001	<.001	3	6
GBM	CD93 →	+0.911	+0.722	.001	.001	3	6
BRCA	COLEC12 →	+0.929	+0.651	.002	.001	3	6
BRCA	FBLN2 →	+1.457	+0.865	<.001	<.001	3	6
BRCA	FBN1 →	+1.257	+0.657	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,026 associations by consensus.

APOA2 vs LYVE1 — BRCA

Explore this scatter interactively →