APOA2

Across TCGA patient cohorts, APOA2 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible APOA2-associated genes across cancer lineages are OR7E53P, UGT2B10, and OR5I1. Each is linked with APOA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both APOA2-to-partner and partner-to-APOA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E53P grouped by APOA2-low versus APOA2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOA2→partner) and Y-score (partner→APOA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR7E53P →	+0.118	+5.292	<.001	.006	3	1
UCEC	UGT2B10 →	+0.596	+4.211	<.001	.009	3	1
UCEC	OR5I1 →	+0.093	+5.226	<.001	.003	3	1
UCEC	MIR8070 →	+1.088	+4.302	<.001	.008	3	1
UCEC	MIR3690 →	+1.039	+4.809	<.001	.003	3	1
STAD	RNU6-439P →	+0.453	+5.105	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

OR7E53P by APOA2 expression — SKCM

Explore this box plot interactively →