APMAP

Across TCGA patient cohorts, APMAP RNA expression is significantly associated with the protein abundance of many other proteins, with 10,150 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible APMAP-associated proteins across cancer lineages are MAVS, TRMT6, and XRN2. Each is linked with APMAP in more than 5 cancer types. Because this analysis shows association rather than direction, both APMAP-to-partner and partner-to-APMAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APMAP versus MAVS in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APMAP→partner) and Y-score (partner→APMAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MAVS →	+0.404	+0.615	<.001	.001	2	6
OV	TRMT6 →	+0.388	+0.574	<.001	.001	3	5
COAD	XRN2 →	+0.327	+0.798	<.001	<.001	3	5
OV	TRMT61A →	+0.319	+0.531	.001	.003	2	5
COAD	KIF16B →	+0.338	+0.469	.001	.004	3	4
COAD	ESF1 →	+0.409	+0.649	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,150 associations by consensus.

APMAP vs MAVS — OV

Explore this scatter interactively →