APMAP

Across TCGA patient cohorts, APMAP protein abundance is significantly associated with the RNA expression of many other genes, with 10,987 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible APMAP-associated genes across cancer lineages are GZF1, NXT1, and ATRN. Each is linked with APMAP in more than 4 cancer types. Because this analysis shows association rather than direction, both APMAP-to-partner and partner-to-APMAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APMAP versus GZF1 in LUAD, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APMAP→partner) and Y-score (partner→APMAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GZF1 →	+0.511	+0.261	.005	<.001	3	5
HNSC	NXT1 →	+0.575	+0.233	.003	.003	3	5
LSCC	ATRN →	+0.713	+0.337	<.001	<.001	3	5
HNSC	TMEM230 →	+0.444	+0.292	<.001	<.001	3	5
OV	TASP1 →	+0.592	+0.338	<.001	.002	3	5
LSCC	TRMT6 →	+0.853	+0.314	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,987 associations by consensus.

APMAP vs GZF1 — LUAD

Explore this scatter interactively →