AP5Z1

Across TCGA patient cohorts, AP5Z1 mutation is significantly associated with the RNA expression of many other genes, with 3,970 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AP5Z1-associated genes across cancer lineages are SNORD126, MIR4510, and VN1R93P. Each is linked with AP5Z1 in more than 3 cancer types. Because this analysis shows association rather than direction, both AP5Z1-to-partner and partner-to-AP5Z1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD126 grouped by AP5Z1-low versus AP5Z1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP5Z1→partner) and Y-score (partner→AP5Z1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	SNORD126 →	+0.506	+4.119	.008	.002	3	4
CESC	MIR4510 →	+0.195	+4.342	<.001	.007	3	3
LIHC	VN1R93P →	+0.118	+5.734	<.001	<.001	3	2
CESC	NF1P10 →	+0.241	+4.569	<.001	.005	3	2
LIHC	CTAG1B →	+0.023	+4.720	.006	.005	3	2
LIHC	BOLA3P4 →	+0.149	+4.525	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,970 associations by consensus.

SNORD126 by AP5Z1 expression — LUSC

Explore this box plot interactively →