AP4S1

Across TCGA patient cohorts, AP4S1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,148 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AP4S1-associated proteins across cancer lineages are SSRP1, FKBP3, and STRN3. Each is linked with AP4S1 in more than 7 cancer types. Because this analysis shows association rather than direction, both AP4S1-to-partner and partner-to-AP4S1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP4S1 versus SSRP1 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AP4S1→partner) and Y-score (partner→AP4S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SSRP1 →	+0.499	+0.581	<.001	<.001	3	8
OV	FKBP3 →	+0.280	+0.404	<.001	.001	3	8
BRCA	STRN3 →	+0.258	+0.356	<.001	<.001	3	8
COAD	SUPT16H →	+0.350	+0.466	<.001	<.001	3	7
PDAC	WDR77 →	+0.258	+0.290	<.001	<.001	3	7
LUAD	PPP4R3A →	+0.268	+0.521	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,148 associations by consensus.

AP4S1 vs SSRP1 — LSCC

Explore this scatter interactively →