Across TCGA patient cohorts, AP4M1 mutation is significantly associated with the RNA expression of many other genes, with 521 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AP4M1-associated genes across cancer lineages are PPIAP38, RNU6-1, and LINC00709. Each is linked with AP4M1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AP4M1-to-partner and partner-to-AP4M1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP4M1→partner) and Y-score (partner→AP4M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PPIAP38 →	+0.140	+4.081	.008	.004	3	3
UCEC	RNU6-1 →	+0.376	+1.778	.005	.004	3	3
COAD	LINC00709 →	+0.107	+5.557	<.001	.001	3	2
SKCM	MTATP6P20 →	+0.065	+4.513	.004	.009	3	2
LUAD	RNU6-340P →	+0.445	+6.584	<.001	.001	3	2
LUAD	RN7SL568P →	+0.350	+5.279	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 521 associations by consensus.

Exploration

AP4M1 survival (RNA) · tumor vs normal (RNA) · all AP4M1 data types