AOX1

Across TCGA patient cohorts, AOX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 23,447 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AOX1-associated proteins across cancer lineages are SNX9, SYNPO2, and OGN. Each is linked with AOX1 in more than 8 cancer types. Because this analysis shows association rather than direction, both AOX1-to-partner and partner-to-AOX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AOX1 versus SNX9 in OV, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AOX1→partner) and Y-score (partner→AOX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SNX9 →	+0.489	+1.184	<.001	.001	3	8
HNSC	SYNPO2 →	+1.016	+1.480	<.001	<.001	3	8
UCEC	OGN →	+1.152	+1.194	<.001	<.001	3	8
BRCA	TNS2 →	+0.389	+1.130	<.001	<.001	3	8
OV	TNS2_S102 →	+0.970	+0.989	<.001	<.001	3	8
UCEC	TNS2_S120 →	+0.554	+0.762	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,447 associations by consensus.

AOX1 vs SNX9 — OV

Explore this scatter interactively →