AOAH-IT1

RNA expression — cross-omics
Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AOAH-IT1 RNA expression is significantly associated with the RNA expression of many other genes, with 9,937 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible AOAH-IT1-associated genes across cancer lineages are AOAH, GVINP1, and PIK3CG. Each is linked with AOAH-IT1 in more than 29 cancer types. Because this analysis shows association rather than direction, both AOAH-IT1-to-partner and partner-to-AOAH-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AOAH-IT1 versus AOAH in LAML, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AOAH-IT1→partner) and Y-score (partner→AOAH-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LAMLAOAH →+2.126+1.685<.001<.001330
DLBCGVINP1 →+1.513+0.400<.001.003227
SKCMPIK3CG →+1.265+0.105<.001<.001326
SKCMIL10RA →+1.687+0.112<.001<.001326
SKCMEVI2B →+1.684+0.117<.001<.001326
SKCMPTPRC →+2.213+0.113<.001<.001326
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,937 associations by consensus.

AOAH-IT1 vs AOAH — LAML

Per-sample scatter of AOAH-IT1 vs AOAH in LAML (Pearson r = 0.85).

Explore this scatter interactively →

Exploration