ANXA8

Across TCGA cell cohorts, ANXA8 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ANXA8-associated genes across cancer lineages are OR2L13, OR2AJ1, and OR2T8. Each is linked with ANXA8 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANXA8-to-partner and partner-to-ANXA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2L13 grouped by ANXA8-low versus ANXA8-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA8→partner) and Y-score (partner→ANXA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR2L13 →	+0.026	+3.043	.002	.006	3	3
OVARY	OR2AJ1 →	+0.033	+3.444	.001	.003	3	2
LUNG_NSCLC_LUAD	OR2T8 →	+0.562	+2.980	<.001	.007	3	2
STOMACH	OR14K1 →	+0.200	+5.285	<.001	.003	3	2
LUNG_NSCLC_LUAD	OR2L3 →	+0.006	+3.189	<.001	.007	3	2
PANCREAS	SLC6A5 →	+0.014	+3.554	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

OR2L13 by ANXA8 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →