ANXA2R

Across TCGA patient cohorts, ANXA2R mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANXA2R-associated genes across cancer lineages are Ku80, MSH2, and p70-S6K. Each is linked with ANXA2R in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA2R-to-partner and partner-to-ANXA2R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by ANXA2R-low versus ANXA2R-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA2R→partner) and Y-score (partner→ANXA2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.299	+2.183	.015	.035	3	1
UCEC	MSH2 →	-0.338	-3.321	.005	.010	3	1
UCEC	p70-S6K →	+0.225	+2.196	.025	.034	3	1
UCEC	PDCD4 →	-0.656	-3.321	.007	.010	3	1
UCEC	STAT3_pY705 →	-0.396	-3.321	.003	.010	3	1
UCEC	CD49b →	-0.347	-3.308	.020	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Ku80 by ANXA2R expression — UCEC

Explore this box plot interactively →