ANXA10

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANXA10 mutation is significantly associated with the mutation status of many other genes, with 707 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANXA10-associated genes across cancer lineages are BAIAP2L1, PNPLA8, and POLR1B. Each is linked with ANXA10 in more than 3 cancer types. Because this analysis shows association rather than direction, both ANXA10-to-partner and partner-to-ANXA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BAIAP2L1 grouped by ANXA10-low versus ANXA10-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA10→partner) and Y-score (partner→ANXA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADBAIAP2L1 →+5.000+4.187.008.00814
UPPER_AERODIGESTIVE_TRACTPNPLA8 →+5.392+5.392.004.00413
LARGE_INTESTINEPOLR1B →+4.159+5.215<.001<.00113
LUNG_NSCLC_LUADSASH1 →+5.584+4.924<.001<.00113
UPPER_AERODIGESTIVE_TRACTAKNA →+5.392+5.392.004.00412
LUNG_NSCLC_LUADADAM7 →+3.584+4.063.003.00312
Each partner links to its Q-omics profile. Showing the 6 strongest of 707 associations by consensus.

BAIAP2L1 by ANXA10 expression — LUNG_NSCLC_LUAD

Box plot of BAIAP2L1 in ANXA10-low vs ANXA10-high samples in LUNG_NSCLC_LUAD.

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Exploration