ANTXR2

Across TCGA cell cohorts, ANTXR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,930 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ANTXR2-associated GO terms across cancer lineages are Urokinase plasminogen activator signaling pathway, Regulation of hemostasis, and Regulation of blood coagulation. Each is linked with ANTXR2 in more than 13 cancer types. Because this analysis shows association rather than direction, both ANTXR2-to-partner and partner-to-ANTXR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Urokinase plasminogen activator signaling pathway grouped by ANTXR2-low versus ANTXR2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ANTXR2→partner) and Y-score (partner→ANTXR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Urokinase plasminogen activator signaling pathway →	+1.173	+1.831	<.001	.002	3	14
BREAST	Regulation of hemostasis →	+0.180	+2.510	<.001	<.001	3	13
BREAST	Regulation of blood coagulation →	+0.178	+2.553	<.001	<.001	3	13
SOFT_TISSUE	Positive regulation of fibroblast proliferation →	+0.150	+3.666	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Positive regulation of focal adhesion assembly →	+0.160	+2.626	.002	<.001	3	13
SOFT_TISSUE	Regulation of protein processing →	+0.173	+2.778	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,930 associations by consensus.

Urokinase plasminogen activator signaling pathway by ANTXR2 expression — LIVER

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