ANTXR2

Across TCGA cell cohorts, ANTXR2 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ANTXR2-associated genes across cancer lineages are OLIG3, XKR4, and HSFY2. Each is linked with ANTXR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANTXR2-to-partner and partner-to-ANTXR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OLIG3 grouped by ANTXR2-low versus ANTXR2-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANTXR2→partner) and Y-score (partner→ANTXR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OLIG3 →	+0.006	+5.000	<.001	.006	3	1
PANCREAS	XKR4 →	+0.059	+5.000	<.001	.006	3	1
LARGE_INTESTINE	HSFY2 →	+0.023	+4.977	<.001	.007	3	1
LARGE_INTESTINE	ARGFX →	+0.020	+6.022	<.001	.001	3	1
BLOOD_Leukemia	FABP12 →	+0.085	+5.201	<.001	.006	3	1
BLOOD_Leukemia	IQCF5 →	+0.121	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OLIG3 by ANTXR2 expression — PANCREAS

Explore this box plot interactively →